The main objective of this article is to indicate whether returns treated as a resource impacts uncertainty in supply chain management. Through an empirical study using the CATI method, the significance of factors that improve the efficiency of return flow in supply chains and the significance of types of uncertainty in supply chain management are presented. The analysis, performed using Pearson’s linear correlation coefficient, indicates relationships and dependencies between variables, such as the drivers of the flow of returns in the supply chain and types of uncertainty. As a consequence of the research and an analysis of its results, it is possible to demonstrate the complexity of the problem, but above all, it is possible to indicate which of the above-mentioned factors affect the reduction of the impact of uncertainty on the supply chain. The presented approach is one of the voices in the ongoing scientific discussion on the management of supply chains under conditions of uncertainty.